eBook - ePub
Dengue Virus Disease
From Origin to Outbreak
Adnan I. Qureshi,Omar Saeed
This is a test
Partager le livre
- 202 pages
- English
- ePUB (adapté aux mobiles)
- Disponible sur iOS et Android
eBook - ePub
Dengue Virus Disease
From Origin to Outbreak
Adnan I. Qureshi,Omar Saeed
DĂ©tails du livre
Aperçu du livre
Table des matiĂšres
Citations
Ă propos de ce livre
Dengue Virus Disease: From Origin to Outbreak provides a detailed accounting of one of the world's fastest growing infections. According to the World Health Organization, Dengue virus incidence has increased 30-fold over the past 50 years, with up to 50 to 100 million infections occurring annually in over 100 endemic countries. This estimate puts nearly half the world's population at risk. This book reviews the history, clinical and diagnostic aspects of dengue virus, also presenting our current knowledge on the pathophysiology of severe dengue and addressing the importance of dengue virus infections in those traveling to parts of the world where it is endemic.
- Covers every important aspect of Dengue virus disease, from biological, to its social and economic impacts
- Highlights the unique aspects of Dengue virus infection and the evolving nature of our understanding of the virus
- Provides a complete description of Dengue virus disease, with details on more recent outbreaks, clinical features, first hand experiences, treatment modalities, and recent novel treatment regimens
- Gives insights into the detailed psychological impact the disease has caused in outbreak regions
Foire aux questions
Comment puis-je résilier mon abonnement ?
Il vous suffit de vous rendre dans la section compte dans paramĂštres et de cliquer sur « RĂ©silier lâabonnement ». Câest aussi simple que cela ! Une fois que vous aurez rĂ©siliĂ© votre abonnement, il restera actif pour le reste de la pĂ©riode pour laquelle vous avez payĂ©. DĂ©couvrez-en plus ici.
Puis-je / comment puis-je télécharger des livres ?
Pour le moment, tous nos livres en format ePub adaptĂ©s aux mobiles peuvent ĂȘtre tĂ©lĂ©chargĂ©s via lâapplication. La plupart de nos PDF sont Ă©galement disponibles en tĂ©lĂ©chargement et les autres seront tĂ©lĂ©chargeables trĂšs prochainement. DĂ©couvrez-en plus ici.
Quelle est la différence entre les formules tarifaires ?
Les deux abonnements vous donnent un accĂšs complet Ă la bibliothĂšque et Ă toutes les fonctionnalitĂ©s de Perlego. Les seules diffĂ©rences sont les tarifs ainsi que la pĂ©riode dâabonnement : avec lâabonnement annuel, vous Ă©conomiserez environ 30 % par rapport Ă 12 mois dâabonnement mensuel.
Quâest-ce que Perlego ?
Nous sommes un service dâabonnement Ă des ouvrages universitaires en ligne, oĂč vous pouvez accĂ©der Ă toute une bibliothĂšque pour un prix infĂ©rieur Ă celui dâun seul livre par mois. Avec plus dâun million de livres sur plus de 1 000 sujets, nous avons ce quâil vous faut ! DĂ©couvrez-en plus ici.
Prenez-vous en charge la synthÚse vocale ?
Recherchez le symbole Ăcouter sur votre prochain livre pour voir si vous pouvez lâĂ©couter. Lâoutil Ăcouter lit le texte Ă haute voix pour vous, en surlignant le passage qui est en cours de lecture. Vous pouvez le mettre sur pause, lâaccĂ©lĂ©rer ou le ralentir. DĂ©couvrez-en plus ici.
Est-ce que Dengue Virus Disease est un PDF/ePUB en ligne ?
Oui, vous pouvez accĂ©der Ă Dengue Virus Disease par Adnan I. Qureshi,Omar Saeed en format PDF et/ou ePUB ainsi quâĂ dâautres livres populaires dans Ciencias biolĂłgicas et MicrobiologĂa. Nous disposons de plus dâun million dâouvrages Ă dĂ©couvrir dans notre catalogue.
Informations
Sujet
Ciencias biolĂłgicasSous-sujet
MicrobiologĂaChapter 1
Dengue virus infection
Adnan I. Qureshi Executive Director, Zeenat Qureshi Stroke Institute, St. Cloud, MN, United States Professor, Department of Neurology at University of Missouri, Columbia, United States
Abstract
The World Health Organization website states âDengue is a mosquito-borne viral disease that has rapidly spread in all regions of World Health Organization in recent yearsâ. In April 2016, World Health Organization issued a conditional recommendation on the use of the vaccine for areas, in which Dengue virus infection is highly endemic, which is defined by population seroprevalence of 70% or higher. Health officials in the Philippines in July 2019 declared a national emergency after a record-breaking 106,630 cases of Dengue fever were reported since January 2019. The World Health Organization (WHO) estimates that 50â100 million Dengue infections occur each year and that almost half the world's population lives in countries where dengue is endemic. This chapter gives a brief introduction into the current Dengue virus epidemic, the role international organizations are playing to prevent spread and future need for more research in treatment and vaccination options.
Keywords
Dengue virus disease; dengue virus infection; research and training in tropical diseases; vaccination; world health organization
Introduction
The World Health Organization website states âDengue is a mosquito-borne viral disease that has rapidly spread in all regions of World Health Organization in recent yearsâ. In April 2016, World Health Organization issued a conditional recommendation on the use of the vaccine for areas, in which Dengue virus infection is highly endemic, which is defined by population seroprevalence of 70% or higher. Dengue virus infection mainly causes a self-limiting flu-like illness and may remain asymptomatic (Fig. 1.1). A reader may wonder why a book should be dedicated to this disease. There are several reasons: 1. The infection can develop into a potentially severe Dengue virus illness which can be fatal and now a major cause of severe illness among children; 2. The disease is increasing exponentially in prevalence; 3. There is no specific treatment for the disease. The global incident map website provides a detailed list of hundreds of Dengue viral illness outbreaks since 2010. The first and last page of the listing is provided to give a better perspective of large number of incident cases in the world. The global map from new Dengue virus disease cases from May 2019 also provides a regional perspective on the disease (Fig. 1.2).
Health officials in the Philippines in July 2019 declared a national emergency after a record-breaking 106,630 cases of Dengue viral fever were reported since January 2019 [1]. This represented a 85% increase than the number of cases in the same period in 2018. Approximately 500 people have died from the Dengue viral illness in 2019. Military hospitals and clinics were put on alert for a possible surge in Dengue viral illness patients [2].
World Health Organization/Department of Control of Neglected Tropical Diseases released a detailed document âThe Global Strategy for dengue prevention and control, 2012â20â. (Fig. 1.3) The executive summary of the document states:
âDengue is a major public-health concern throughout tropical and sub-tropical regions of the world. It is the most rapidly spreading mosquito- borne viral disease, with a 30-fold increase in global incidence over the past 50 years. The World Health Organization (WHO) estimates that 50â100 million Dengue infections occur each year and that almost half the world's population lives in countries where dengue is endemic. In some countries, the burden of dengue is comparable to that of tuberculosis and other communicable diseases with high disease burdens; unexpected surges in cases and the challenge to health systems of triaging thousands of cases without knowing which severe cases will require hospital care are additional challenges ⊠This Global strategy for dengue prevention and control, 2012â20 aims to address this need.
Dengue morbidity can be reduced by implementing improved outbreak prediction and detection through coordinated epidemiological and entomological surveillance; promoting the principles of integrated vector management and deploying locally-adapted vector control measures including effective urban and household water management. Effective communication can achieve behavioural outcomes that augment prevention programmes.
Research will continue to play an important role in reversing the trend in dengue, a neglected tropical disease, by improving methods and systems for surveillance, prevention and control.
Reversing the trend requires commitments and obligations from partners, organizations and countries, as well as leadership by WHO and increased funding. Dengue prevention and management can now exploit opportunities presented by promising advances in vector control technology interventions, diagnostics, prognostic systems for triage, evidence-based clinical interventions and candidate vaccine developments.â
TDR, the Special Program for Research and Training in Tropical Diseases, which is a scientific collaboration supports efforts to combat diseases of poverty has a dedicated section on Dengue virus disease. The program was developed by World Health Organization, and is sponsored by the United Nations Children's Fund, the United Nations Development Program, and the World Bank. On the programs by TDR is the web based tool âOperational Guide: The Early Warning and Response System (EWARS) for Dengue Outbreaksâ which acts as a resource for: (i) analysis of historic dengue datasets; (ii) identify appropriate alarm indicators that can predict forthcoming outbreaks; and (iii) use these results and analyses to build an early warning system to detect dengue outbreaks (Fig. 1.4). Another handbook by TDR âTechnical handbook for dengue surveillance, dengue outbreak prediction/detection and outbreak responseâ provides a âmodel contingency planâ is to assist program managers and planners in developing a Dengue virus illness outbreak response plan through clearly defined and validated alarm signals and organize an early response âemergency responseâ once an outbreak has started (Fig. 1.5).
Another controversy is whether donated blood should be screened for presence of Dengue virus [3]. Dengue virus like West Nile virus and Chikungunya virus may be transmitted through blood transfusions. One study tested 15,350 blood donation samples; Dengue virus RNA was detected in 29 samples for a prevalence of 1 per 529 (0.19%). Dengue virus types 1, 2, and 3 with viral titers of 105â109 copies/mL were detected by type specific reverse transcriptase polymerase chain reaction in 12 samples of which all were infectious in mosquito culture [4]. Another study in Portugal found that 43 of 1948 blood donations tested positive for Dengue virus genome (further identified as Den...