
- 348 pages
- English
- PDF
- Available on iOS & Android
PCR: Methods Express
About this book
PCR is the most widely used technique in molecular biology. New PCR variants offering substantial benefits to existing protocols appear on a frequent basis. PCR: Methods Express describes the very latest PCR-based methodologies and approaches to provide the most up-to-date practical advice on how to tackle a broad range of biological problems including: *real time qRT-PCR
*rapid generation of gene targeting constructs
*PCR multiplexes
*PCR-based mutagenesis
*identification of microdeletions and microduplications*DNA methylation analysis
*forensic genetic DNA typing
*genotyping
*identification of mutations in single cells
*whole genome amplification
*diagnosis of infectious diseases
*inverse PCR-based RFLPThis book is a comprehensive research guide; every chapter discusses the merits and limitations of the available approaches and then provides fully-proven protocols with hints and tips for success. PCR: Methods Express is an essential laboratory manual for researchers in all life science fields and at all levels, from postgraduate student to principal investigator.
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Table of contents
- Contents
- Color Section
- CHAPTER 1: An introduction to the polymerase chain reaction
- CHAPTER 2: Polymerases for PCR
- CHAPTER 3: A detailed guide to quantitative RT-PCR
- CHAPTER 4: Use of quantitative PCR for the detection of genomic microdeletions or microduplications
- CHAPTER 5: Robust and unique PCR for single-nucleotide polymorphism genotyping applications
- CHAPTER 6: Using PCR and linkage mapping to identify single genes and quantitative trait loci for livestock traits
- CHAPTER: 7 PCR restriction fragment length polymorphism analysis for genotyping of single-nucleotide polymorphisms
- CHAPTER 8: Forensic genetic DNA typing with PCR-based methods
- CHAPTER 9: Large PCR multiplexes with special reference to forensic single-nucleotide polymorphism typing
- CHAPTER 10: Pre-implantation genetic diagnosis of monogenic disease...
- CHAPTER 11: Rapid generation of gene-targeting constructs
- CHAPTER 12: Construction of long DNA molecules from multiple fragments using PCR
- CHAPTER 13: Efficient PCR-based mutagenesis method applicable to diverse mutagenesis strategies using type IIs restriction enzymes
- CHAPTER 14: Inverse PCR-based restriction fragment length polymorphism for identifying low-level mutations in tumors
- CHAPTER 15: PCR methods for infectious disease diagnosis
- CHAPTER 16: Use of PCR for DNA methylation analyses
- CHAPTER 17: PCR-based methods to determine DNA methylation status...
- CHAPTER 18: PCR-based whole genome amplification
- CHAPTER 19: PCR sequencing of human genes for the discovery of DNA sequence variants
- APPENDIX 1 List of suppliers
- Index