Medical Pharmacology at a Glance
Michael J. Neal
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Medical Pharmacology at a Glance
Michael J. Neal
About This Book
The internationally best-selling Medical Pharmacology at a Glance is the ideal companion for all medical and healthcare students, providing a visual overview of pharmacology, and describing the basic principles of drug action, interaction, absorption, and excretion. Clear and accessible chapters organised around common diseases and conditions facilitate efficient clinical learning, and include references to drug classes and side effects, disease pathophysiology, prescribing guidelines, and more.
Now in its ninth edition, this leading guide has been thoroughly updated to reflect current guidelines and drug information. This edition features new and revised illustrations, additional pedagogical tools, and enhanced online content. Widely recognised as both the best introduction to medical pharmacology and the perfect revision tool for USMLE and pharmacology exams, this invaluable guide:
- Covers a wide range of drugs used to treat conditions such as hypertension, anaemias, cancer, and affective disorders
- Explains drug mechanisms and the principles of drug action
- Discusses practical topics including drug misuse, drug indications, and side effects
- Includes a companion website featuring online cases, flashcards, and a list of core drugs
Frequently asked questions
Information
1
Introduction: principles of drug action
- pharmacodynamics â the effects of the drug on the body; and
- pharmacokinetics â the way the body affects the drug with time (i.e. absorption, distribution, metabolism and excretion).
Receptors
- Agonist (ligand)âgated ion channels are made up of protein subunits that form a central pore (e.g. nicotinic receptor, Chapter 6; Îłâaminobutyric acid (GABA) receptor, Chapter 24).
- Gâproteinâcoupled receptors (see below) form a family of receptors with seven membraneâspanning helices. They are linked (usually) to physiological responses by second messengers.
- Nuclear receptors for steroid hormones (Chapter 34) and thyroid hormones (Chapter 35) are present in the cell nucleus and regulate transcription and thus protein synthesis.
- Kinaseâlinked receptors are surface receptors that possess (usually) intrinsic tyrosine kinase activity. They include receptors for insulin, cytokines and growth factors (Chapter 36).