Advanced Topics in Forensic DNA Typing: Methodology

John M. Butler

• Publisher: Academic Press
• Year: 2011
• Print ISBN:
  9780123745132
• eBook ISBN:
  9780123878236
• Topic: Social Sciences
• Subtopic: Forensic Science
• Index: Social Sciences

Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience.  This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues. - Contains the latest information - hot-topics and new technologies - Well edited, attractively laid out, and makes productive use of its four-color format - Author John Butler is ranked as the number one "high-impact author in legal medicine and forensic science, 2001 to 2011" by ScienceWatch.com

Table of contents

• Cover image
• Table of Contents
• Front-matter
• Copyright
• Dedication
• Foreword
• Introduction
• Acknowledgments
• About the Author
• Chapter 1. Sample Collection, Storage, and Characterization
• Chapter 2. DNA Extraction Methods
• Chapter 3. DNA Quantitation
• Chapter 4. PCR Amplification
• Chapter 5. Short Tandem Repeat (STR) Loci and Kits
• Chapter 6. Capillary Electrophoresis
• Chapter 7. Quality Assurance and Validation
• Chapter 8. DNA Databases
• Chapter 9. Missing Persons and Disaster Victim Identification Efforts
• Chapter 10. Degraded DNA
• Chapter 11. Low-Level DNA Testing
• Chapter 12. Single Nucleotide Polymorphisms and Applications
• Chapter 13. Y-Chromosome DNA Testing
• Chapter 14. Mitochondrial DNA Analysis
• Chapter 15. X-Chromosome Analysis
• Chapter 16. Non-human DNA
• Chapter 17. New Technologies and Automation
• Chapter 18. Legal Aspects of DNA Testing and the Scientific Expert in Court
• Appendix 1. Reported Sizes and Sequences of STR Alleles
• Appendix 2. Familial DNA Searches: Potential, Pitfalls, and Privacy Concerns
• Appendix 3. List of Suppliers for DNA Instruments, Reagents, Services
• Appendix 4. Interviews Supporting Legal Aspects of DNA Testing
• Subject Index