eBook - ePub
Cell Biology E-Book
Thomas D. Pollard, William C. Earnshaw, Jennifer Lippincott-Schwartz, Graham Johnson
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- 908 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Cell Biology E-Book
Thomas D. Pollard, William C. Earnshaw, Jennifer Lippincott-Schwartz, Graham Johnson
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About This Book
The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today's students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time.
- Clearly written format incorporates rich illustrations, diagrams, and charts.
- Uses real examples to illustrate key cell biology concepts.
- Includes beneficial cell physiology coverage.
- Clinically oriented text relates cell biology to pathophysiology and medicine.
- Takes a mechanistic approach to molecular processes.
- Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing.
- Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation.
- Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing.
- Includes hundreds of new and updated diagrams and micrographs, plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail.
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Index
Page numbers followed by “f” indicate figures, “t” indicate tables, and “b” indicate boxes.
A
A kinase-anchoring proteins (AKAPs), 429
A site of tRNAs, 213
AAA ATPase family, 623, 623f, 625b, 636f
Aa-tRNA synthetases, Aminoacyl-tRNA (aa-tRNA) synthetases
A-band, 673f
Abasic sites, 750
ABC transporters, 244t, 250–252, 250f–251f, 346–347, 347f
degradation by proteasomes and, 401
protein translocation across plasma membrane by, 311, 314f
type I, 314f, 315
ABP-280, 590t–591t
Abp1p, 590t–591t
Abscission, 771f, 775–776, 776f–777f
Accidental cell death, 798, 798b
programmed cell death vs., 797–800, 797f–800f
Acetylated N-terminus, 34f
Acetylcholine (ACh), 291f, 295
neuromuscular junctions and, 294
skeletal muscle contraction and, 678
Acetylcholine (ACh) receptors, 294
muscarinic, 293–294
nicotinic, 273–275, 274f, 279
Acetylcholinesterase, 294
Acetyl-CoA, 319, 321f
ACh, Acetylcholine (ACh)
ACh receptors, Acetylcholine (ACh) receptors
Achiasmate segregation, 785
Acrosomal process, 652f, 666f
Actin, 575–576, 576f
bulk movement of cytoplasm driven by, 647–648, 648f–649f
contractile ring of, 771–772
critical concentration of, 579–580
dynamics of, in live cells, 585–588, 586b, 586f, 588f
evolution of, 577–578, 578f
molecule of, 577, 577f
movements of organelles based on, 648–649, 649f
polymerization of, 579–58...