Chapter 1
Nostalgia in 1688
Home is where one starts from.
T. S. ELIOT, East Coker (1940)
Johannes Hoferâs 1688 Dissertatio medica de nostalgia, oder Heimwehe was perhaps destined to never feature in medical history textbooks. This was, after all, but the work of a medical student who chose to write on a disease no one had then heard of, and that we would be hard pressed to find in any medical taxonomy today. An unlikely medical maverick, Hofer cannot be credited with any lasting contribution to the Western medical tradition, despite serving the profession diligently throughout his life as a general practitioner in his hometown of Mulhouse. Nevertheless, he did bequeath to posterity a term that has, for better or worse, become second nature to modern lifeâalmost a âkeywordâ in its own right, but one with a little-known medical genesis. The quest to understand where our modern infatuation with nostalgia comes from must therefore begin with the termâs unlikely inventor and the clinical hypotheses of a nineteen-year-old.
As Jean Starobinski remarks, by providing a scientific name for and full clinical description of what had hitherto been a vernacular category, Hofer transformed âan emotional phenomenon [Heimweh] into a medical phenomenon [nostalgia].â1 Why he did so, and what this says about the time in which he lived, are the questions this chapter seeks to elucidate. Briefly put, my argument is twofold: that seventeenth-century clinical breakthroughs and evolving medical theories enabled Hofer to conceive of nostalgia in a way that closely resembled contemporary understandings of melancholia and other emotional disorders; but that medical transformations alone cannot account for the perceived need to devise a new diagnostic category (rather than use an existing one). As a detailed exegesis of Hoferâs remarkable text reveals, the making of nostalgia did not proceed directly from an epidemiological revolution or one of the many discoveries that overhauled Western medicine in the age of scientific revolution. Rather, to grasp its conditions of possibility we must cast our net further afield, beyond medicine itself, to the broader social, political, and intellectual forces that shaped Hoferâs life and that of his contemporaries. Nostalgia, it turns out, was born of a time of conflict and generalized instability, a âGeneral Crisisâ that rocked much of Europeâand the upper Rhineland in particularâthroughout the seventeenth century.
An Unlikely Medical Maverick
Johannes Hofer was born in the Alsatian town of Mulhouse on May 2, 1669, the last of twelve siblings in a prosperous family of prominent local pastors. We know little of his childhood, other than the fact of his fatherâs premature death when Johannes was only six years old. It certainly was stern and studious in keeping with Mulhouseâs official Calvinist piety. Most likely, it also taught the young man the proud history of his hometown, an independent and staunchly republican enclave within the Holy Roman Empire since the fourteenth century. Hofer would already have been well versed in humanist, moral, and civic traditions when, barely a teenager, he followed his ancestorsâ footsteps to continue his studies in the neighboring town of Basel, home to the first Swiss university. He read philosophy and theology for three years and, in 1685, opted to heal bodies rather than souls by enrolling in medical school.2 As it turned out, he would end up curing both.
Established by papal bull in 1459, the University of Basel emerged out of the wars of religion as a leading institution of higher education in Protestant Europe, attracting students from nearby Rhineland and German states. Its medical faculty courted controversy in 1527 when Paracelsus famously burned Avicennaâs Medical Canon (the main reference work of medieval medicine), but thereafter became a reputable center for learning, book printing, and the liberal humanism typical of reformed cities. For much of the seventeenth century, the dominant natural philosophy taught in Basel was an eclectic synthesis of Aristotelianism and Ramism, the iconoclastic body of thought developed by the Huguenot Petrus Ramus (who also lectured at the university before being murdered during the St. Bartholomewâs day massacre). Medieval scholasticism was therefore already on the defensive when Cartesianism was introduced into the classrooms in the 1660s, prompting a major curricular reorientation toward empiricism and new chemical and physical explanatory models.3
When Hofer matriculated in 1685, he therefore entered an institution and a larger medical profession undergoing unprecedented transformations. He found close mentors in two junior professors, both graduates of the medical school: Jacob Harder, who taught rhetoric and physics before claiming the chair of anatomy and botany in 1687 (the lowest of three full professorships, after those of medical theory and medical practice); and Theodor Zwinger, the scion of an important family of doctors from Basel, who held the chair of eloquence during Hoferâs studies, before also moving on to the chairs of anatomy and practical medicine thereafter. By the mid-1680s Harder and Zwinger had become established experimental researchers and Baselâs leading advocates of the âiatromechanicalâ and âiatrochemicalâ challenge to orthodox humoral medicine.4 Based on the facultyâs course catalog, Hoferâs biographer has estimated that the young student spent the bulk of his training learning about brain anatomy, the organs of the senses, organic viscera, and experimental chemistry with his professors.5 It is almost certainly in these classes that he was exposed to Descartesâs mechanistic philosophy and to important discoveries in brain anatomy, physiology, and neurologyâall of which transpire in his written work. Hofer prepared his thesis on nostalgia under Harderâs guidance and defended it on June 22, 1688, in the manner of a âdisputationâ (disputatio), or a formalized debate with his professors (Harder, Zwinger, and the chairs of theoretical and practical medicine). This was only a preliminary requirement, submitted in preparation for the final examination and inaugural thesis, the disputatio medica inauguralis, which Hofer filed the following April on the somewhat less esoteric topic of uterine dropsy (De hydrope uteri).
As is often the case with early modern medical dissertations, it is difficult to establish beyond all doubt that the text actually is Hoferâs work. Twenty-first-century notions of authorship do not apply to a time when it was customary for professors and students to work collaboratively and share the honors. Typically, the former would write the text, whereas the latter would present and defend its claims in a public disputation. (This was especially useful for testing daring new ideas.)6 While it is, therefore, possible that Harder authored parts of the thesis, it does seem that Hofer was the primary authorial voice as he is clearly identified as âauthorâ and not just as ârespondent.â Moreover, he explicitly chose to present his research as a dissertatioâthen a relatively new term conveying research based on hypotheses and empirical observationsârather than a more conventional disputatio (a codified recital of canonical knowledge).7
Whatever their exact contribution to the text itself, it is clear that Harder and Zwinger shaped Hoferâs medical training and helped him launch his career as a doctor through their connections. Harder made sure that his studentâs thesis was published by a local printing press, Jacob Bertsch (an unusual accolade for a preliminary work).8 The text was subsequently reissued in revised form in a collection of notable dissertations that Zwinger edited in 1710. In fact, multiple editions would continue to be reprinted periodically, long after Hofer had moved back to Mulhouse and bracketed his medical vocation for a highly successful career in municipal politics. Intriguingly, several of these circulated under modified titles and were more or less explicitly attributed to Harder. As we will see in the next chapter, the vicissitudes of this âuncertain diseaseâ (as nostalgia would come to be described) may be attributed at least in part to the editorial innuendo that clouded the diseaseâs paternity for much of the eighteenth century and beyond.
Heimweh to Nostalgia
Authorial conundrums aside, Hoferâs De Nostalgia is, in and of itself, a puzzling text that defies easy categorizations.9 At first sight, it appears to be a rather conventional example of the research produced by seventeenth-century European medical faculties. Its sixteen octavo pages of Latin prose are standard for the time, and its style is that of someone trained in the classical rhetorical and philosophical traditions. It bears formal similarities with countless other medical disputationes, including an elaborate dedication to the presiding professors and an annex (corollaria) of laudatory remarks and poems on the student by acquaintances. Its content is, likewise, straightforward enough: after providing a rationale for his choice of topic (Thesis I), Hofer defines his object of study by naming the condition (§II) and outlining its basic pathogenesis (§III). He subsequently presents two cases studies (§IV) and details the clinical picture with a discussion of predisposing factors (§V), the seat of the disease (§VI), its etiologyâboth internal (§VII) and external causes (§VIII)âand symptomatology (§IX). He concludes by revisiting the conditionâs pathophysiology (§X), its prognosis (§XI), and therapeutic recommendations (§XII).
Still, identifying a new disease is no ordinary feat, and it would be unfair to dismiss Hoferâs dissertation as wholly unoriginal. In more ways than one, he epitomized what Roger French has called the âlearned and rational doctorâânamely, the university-trained physician, mindful of tradition but increasingly versatile and at ease in the rapidly changing world of seventeenth-century medicine.10 Hofer certainly was no iconoclast, but he showed a keen interest in the pioneering experimental work of his time and was savvy enough to couch his findings in tentative terms. He explained his original topic choice as a matter of curiosity about mysterious stories of youngsters who succumbed to ill-defined âfeversâ and âconsumptionâ far from home. The Swiss, Hofer noted, already knew the disorder by the vernacular term âdas Heim-weh,â literally âhome-sickness.â The French also spoke of âla maladie du paysâ to describe the âsorrow caused by the lost charm of the native landâ among Swiss expatriates (§I). Neither of these terms, however, was scientific enough to properly define a disease (morbo). Hofer hesitated over the all-important task of naming this new clinical entity, at one point considering other neologisms such as ânosomaniaâ (literally âreturn-madnessâ) and the more descriptive âphilopatridomaniaâ (âmadness caused by yearning for the homelandâ). His preference, though, lay with a third coinage, less precise but still sufficiently savant and decidedly more pleasing to the ear: âÎÎΣ΀ÎÎÎÎÎ,â or ânostalgia,â from the Greek roots ÎœÏÏÏÎżÏ, or nostos (homecoming), and ΏλγοÏ, or algos (pain or longing). Nostalgia, Hofer boldly asserted, would stand for the deep âsadness [tristem animum] arising from the burning desire to return to the homelandâ (§IIâIII).
A counterfactual history could fruitfully speculate on what the termâs trajectoryâand, perhaps, modernityâs course itselfâmight have been had Hofer, or his professors, finally opted for a more unwieldy term. Be that as it may, the choice of ânostalgiaâ was crucial not only because more euphonic, but because it distinguished the condition from conventional forms of madness. For Hofer, homesickness did not affect oneâs reason or intellect as a whole, and it was not a particular kind of âmaniaâ or a âfrenzy.â Although it clearly entailed psychological suffering and sometimes even showed signs of âmelancholic deliriumâ (delirii melancholici) (§III), as far as he could tell, it only targeted discrete mental faculties. But whereas a twenty-first-century reader might expect him to have singled out a faulty memory as the source of the ill, Hofer had another mental operation in mindâone that seemed most consonant with nostalgiaâs ostensibly spatial, rather than temporal, coordinates. As he repeatedly made clear to his readers, nostalgia had to be understood first and foremost as the âsymptom of a disordered imaginationâ (symptoma imaginationis laesae) (§III).
Hofer described the pathogenic process at the heart of the condition in the typical language of late seventeenth-century physiology. He posited that what troubled the imagination was the âconstant movement of the animal spirits along the white tubules of the striate bodies and oval center of the brainâ (§XI), where âresidual impressions of the homeland [patriae] adhereâ (§VII). Sensory stimulation induced this vibration, soliciting the imaginative faculties to converge on mental images [phantasmata] impressed in memory, and âexcite in the soul [anima] a recurring and exclusive idea of returning to the homelandâ (§III). Hofer viewed these vibrating spirits in corpuscular terms, as a quantifiable flow of fine particles that surged along nervous conduits setting in motion a chain reaction with both psychic and somatic consequences. The mindâs fixation on the idea of home blocked the actual flow of animal spirits, preventing them from sustaining the âvibration of the fibrils in the common sensorium [sensorio communi]â necessary to the proper functioning (multitasking) of the brain. Because of this hoarding, the spirits also could not flow in sufficient quantities âalong the invisible channels that connect the various parts of the body,â thus affecting all other natural faculties. Hofer singled out loss of appetite and poor digestion due to diluted gastric juices, leading to an overly acidic chyle that would, in turn, yield viscous serum and thick lymph when mixed with blood. The end result was an overconsumption of animal spirits in the brain and lackluster regeneration of the same spirits in the blood, thus further slowing down all bodily and mental functions. In an advanced case, blood would begin to thicken and clot, hindering circulation and affecting the heart. At this stage the nostalgic patient might begin to develop aggravating somatic conditions, including bouts of anxiety, fever, and obstruction of the glands (§X). Hoferâs full symptomatology reads like a laundry list of morbid signs: âconstant sadness [tristia continua], obsessive thinking about the homeland, insomnia and agitated sleep, general weakness, loss of appetite, heart palpitations, respiratory difficulties, [ . . . ] continuous and intermittent feversâ (§IX). His prognosis left little room for hope: if nostalgia was allowed to fester untreated, the âconsumption of the spiritsâ and inexorable weakening of the body would hasten death by exhaustion (§XI).
Hofer embedded this detailed pathophysiological explanation within a more tentative examination of nostalgiaâs broader epidemiology based on personal and related observations in his entourage. He started by distinguishing between preexisting chronic and acute conditions that might predispose to nostalgia on the one hand, and the difficulties encountered when trying to adapt to a change in lifestyle or habits following expatriation on the other. The latter clearly interested him most, and he singled out unfamiliar customs and foods, a marked change in atmosphere, and insults professed in a foreign language as possible triggers. A âhomebound educationâ with little contact with the outside world, he claimed, was certain to produce socially inept adolescents incapable of âadapting to foreign ways of lifeâ or, for that matter, of âforgetting their motherâs milk.â Hofer seems to have been uncomfortable with circulating rumors that Heimweh was a particularly Swiss maladyâa topos emphasized at the end of his thesis, in a few short verses by the French Huguenot Charles Ancillon, who congratulated the author on having shown that a Swiss could cure what he described as a ânational malady.â Despite only having Swiss examples at hand to rely upon, Hofer invoked the findings of other doctors across Europe to recuse the idea that this was a Schweizerkrankheit (and one that targeted the Bernese in particular). Why they seemed especially prone Hofer wasnât quite sure, although he recognized that the predisposing factors seemed to apply particularly well to isolated alpine communities. Most interestingly, he s...