eBook - PDF
Methods in Molecular Biophysics
Structure, Dynamics, Function for Biology and Medicine
- English
- PDF
- Available on iOS & Android
eBook - PDF
Methods in Molecular Biophysics
Structure, Dynamics, Function for Biology and Medicine
About this book
Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.
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Yes, you can access Methods in Molecular Biophysics by Nathan R. Zaccai,Igor N. Serdyuk,Joseph Zaccai in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biophysics. We have over one million books available in our catalogue for you to explore.
Information
Tetrahymena
,
373
–
374
tetramethylsilane
(TMS),
556
–
558
thermal
energy,
5
,
9
,
59
–
61
,
66
,
147
,
169
,
193
–
194
,
255
–
256
,
414
,
419
,
441
,
531
,
535
thermionic
electron
gun,
494
thermophile,
17
hyperthermophile,
17
thermosome,
444
third
law
of
thermodynamics,
119
Thomson
factor.
See
scattering
amplitude
or
length,
electron
three-photon
excitation,
387
thymine,
27
,
33
,
265
,
317
tilt
pair,
506
tilt
transfer
function,
503
time
correlation
function,
232
,
242
,
533
,
604
time
of
fl
ight
(TOF)
mass
spectrometer,
71
,
80
–
81
,
94
,
107
time
of
fl
ight
(TOF)
neutron
scattering,
539
–
540
time-averaged
fl
uctuation,
441
time-resolved
crystallography,
408
,
463
,
483
time-resolved
fl
uorescence
spectroscopy,
216
,
219
time-resolved
Raman
spectroscopy,
301
,
302
,
303
tip
angle,
569
TIRFM.
See
total
internal
re
fl
ectance
fl
uorescence
microscopy
tomography,
499
,
502
,
629
,
635
,
637
–
638
topoisomerase,
367
–
369
total
internal
re
fl
ectance
fl
uorescence
microscopy
(TIRFM),
384
,
388
toxin
cholera
toxin,
37
,
39
diphtheria
toxin,
31
–
32
Shiga
toxin,
39
tracer
diffusion
coef
fi
cient,
166
transcription,
26
,
33
–
34
,
104
,
212
,
347
,
351
–
352
,
358
,
360
,
592
,
617
,
620
transducer,
180
,
368
,
643
–
646
translational
diffusion,
53
,
161
,
165
,
168
,
175
,
229
–
230
,
236
–
239
,
535
,
537
,
602
,
606
,
608
coef
fi
cient,
166
,
177
transmission
electron
microscopy,
107
,
348
,
490
,
494
,
502
transverse
relaxation
time,
553
–
554
,
575
,
607
transverse
relaxation-optimized
spectroscopy
(TROSY),
546
,
580
,
583
–
584
,
596
–
597
,
614
trapping
of
intermediate
states,
483
Treatise
on
Light
(Huygens),
407
,
410
trehalose,
61
,
64
,
319
,
536
triple
isotopic
substitution
method,
441
triple-axis
spectrometer,
408
,
532
,
538
–
539
triplet
relationship
(in
crystallography),
474
tropomyosin,
199
,
209
TROSY.
See
transverse
relaxation-
optimized
spectroscopy
twinning,
crystal,
467
two-dimensional
(2D)
NMR,
281
,
546
,
579
–
581
,
585
two-dimensional
infrared
(2D-IR)
spectroscopy,
8
,
281
–
285
two-photon
excitation,
246
,
384
–
387
,
392
two-state
reaction
or
conversion,
257
ultrasound
imaging,
448
,
639
,
642
–
643
,
645
,
648
unbending
procedure,
507
uncertainty
principle,
Heisenberg
’
s,
56
,
61
,
551
underfocus,
495
,
503
unit
cell
(de
fi
nition),
416
unstructured
protein,
311
,
616
–
618
uracyl,
33
,
265
UV-absorbing
matrix,
71
,
108
UV
–
visible
spectral
range,
188
,
254
–
258
,
260
,
266
,
297
virus
blue
tongue
virus,
482
herpes
simplex
virus
(HSV),
500
,
506
respiratory
syncytial
virus
(RSV),
620
Semliki
forest
virus,
502
,
512
–
513
viscometer
Couette
viscometer,
179
Ostwald
viscometer,
179
Ubbelohde
viscometer,
179
water
structure,
19
,
21
–
22
,
132
Watson
–
Crick
base
pair,
35
wave
interference,
533
wave
nature
of
light,
326
,
407
wave
number,
266
–
267
,
269
,
271
,
273
,
277
,
288
,
299
wave
vector,
46
,
52
,
55
,
150
,
233
,
283
,
410
,
413
,
415
,
532
wave
–
particle
duality,
55
weak
phase
object,
492
Wehnelt
cylinder,
494
Weiner
correction,
504
Weissenberg
camera,
483
,
485
Wilson
distribution,
478
Wilson
plot,
466
,
478
,
511
Wilson
statistics,
466
worm-like
chain,
368
,
376
X-ray
absorption,
255
,
295
,
409
,
476
,
632
–
633
X-ray
detector,
421
,
494
X-ray
free
electron
laser
(XFEL),
463
–
464
X-ray
generator,
420
X-ray
photon,
409
,
419
,
421
,
464
,
631
,
633
,
635
X-ray
pulse,
463
,
484
X-ray
wavelength,
8
,
465
,
476
yellow
fl
uorescent
protein
(YFP),
399
YFP.
See
yellow
fl
uorescent
protein
zero
point
energy,
61
zeroth
law
of
thermodynamics,
117
zinger,
468
Subject
Index
684
Table of contents
- Cover
- Half-title
- Reviews from the First Edition
- Title page
- Copyright information
- Dedication
- Contents in Brief
- Table of Contents
- Preface to the First Edition
- Preface to the Second Edition
- Introduction: Molecular Biophysics at the Beginning of the Twenty-First Century: From Ensemble Measurements to Single-Molecule Detection
- A Biological Macromolecules and Physical Tools
- B Mass Spectrometry
- C Thermodynamics
- D Hydrodynamics
- E Optical Spectroscopy
- F Optical Microscopy
- G X-ray and Neutron Diffraction
- H Electron Diffraction
- I Molecular Dynamics
- J Nuclear Magnetic Resonance
- K Medical Imaging
- References
- Author Index
- Subject Index